Posted on November 7, 2009 by nanocolors
Posted on November 7, 2009 by nanocolors
The Hadassah Medical Organization plan to start in January 2010 a phase I clinical trial entitled “Antibacterial properties of silicon incorporated with quaternary ammonium polyethylenimine nanoparticles” now registered in the Clinicaltrials.gov database under reference NCT01007240. According to this page, “the aim of this study is to evaluate the antibacterial activity of crosslinked quaternary ammonium polyethylenimine (PEI) nanoparticles incorporated at 1-2% w/w in a commercial soft liner material when compared to the commercial soft liner material“.
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Posted on November 4, 2009 by nanocolors
Posted on November 4, 2009 by nanocolors
Here are two useful sources of information for getting a feeling of the ongoing French nanotech debate :
- videos related to the debate, including video summaries of some of the public meetings are available here ;
- slideshare versions of presentations delivered at the meetings are available here ; although very short (too short to my mind), some provide interesting elements.
[[[ Additional link suggested by Nanocolors :
# Program of the French nanotech debate ]]]
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Posted on November 4, 2009 by nanocolors
This chart was built by searching the Espacenet database for patents mentionning the prefixes “nano” and “paint” in their title or abstract.

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Posted on October 29, 2009 by nanocolors
Posted on October 25, 2009 by nanocolors
This chart was built by searching PubMed for publications mentionning iron oxide nanoparticles in their title or abstract.

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Posted on October 25, 2009 by nanocolors
A new assay developped by US and Austrian researchers uses gold nanoparticles and DNA as amplification agents to detect prostate specific antigen (PSA), a protein associated with prostate cancer. The immunoassay is based on the use of 1) PSA antibody-functionalised gold nanoparticles decorated with DNA strand and 2) magnetic microparticles functionalised with a second PSA antibody. In solution, these two particles both bind to PSA ; the probes can then be magnetically separated thanks to the presence of the magnetic particles. DNA is then cleaved from the gold nanoparticles surface and its quantity (measured owing to a scanometric assay) indirectly indicates the level of PSA initially present in the sample. According to the researchers, this assay is ~300 times more sensitive than other commercial assays (see for example this article for more details).
[[[ Additional links suggested by Nanocolors :
# Gold nanoparticles in biomedical publications since 2000
# Functionalized nanoparticles in patents since 2000
# Gold nanoparticles for cancer detection animation ]]]
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Posted on October 24, 2009 by nanocolors
Posted on October 18, 2009 by nanocolors
This chart was built by searching PubMed for publications mentionning PLGA nanoparticles in their title or abstract (PLGA stands for PolyLactic-co-Glycolic Acid).

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