Chitosan nanoparticles : volumetry in biomedical publications since 2000

This chart was built by searching PubMed for publications mentionning chitosan nanoparticles in their title or abstract.

Modified phytoglycogen nanoparticles to protect oil in foods from oxidation

A researcher from Purdue University sucessfully modified the surface of phytoglycogen nanoparticles to make them behave “like an emulsifier, creating phytoglycogen octenyl succinate, or PG-OS. PG-OS is thicker and denser than commonly used emulsifiers, creating a better defense from oxygen, free radical and metal ions, which cause lipid oxidation“. His work also showed that ε-polylysine, a polypeptide much smaller than the PG-OS nanoparticles, can be added to the oil droplets to aid in the protection from oxidation : “PG-OS nanoparticles with ε-polylysine significantly increased the amount of time it took for oxidation to ruin the oil droplets, in some cases doubling the shelf life of the model product“. The main applications of these findings would be in systems  in which the oxidation of lipids is a concern, especially in the food, cosmetics, or nutritional supplement industries (article).

Video interview : the biomedical attraction of magnetic nanoparticles

In this video interview, Kevin O’Grady, professor of physics at the University of York and magnetic materials specialist, provides an overview of the fundamental science of magnetic nanoparticles and their potential for diagnostic and therapeutic applications.

[[[ Additional link suggested by Nanocolors :

# Magnetic nanoparticles : volumetry in patents since 2000 ]]]

Focus on nanotech companies in the biomedical sector

This post focuses on companies specifically developping/proposing nanotech-based products & applications in the biomedical sector ; for each company listed below the specific area of activity and/or a flagship product or application are also mentionned :

<> BIND Biosciences (USA) : therapeutic targeted nanoparticles

<> BioNanomatrix (USA) : nanochannel array technology for genome analysis

<> Calando Pharmaceuticals (USA) : RNAi/Oligonucleotide Nanoparticle Delivery (RONDEL) technology

<> Cerulean Pharma (USA) : Nanocell nanobiology platform for multi-compartmental nanoparticle-based therapeutics

<> Cromoz (USA) : water soluble carbon nanotubes and water soluble fluorescent carbon quantum dots for the biomedical industry (drug delivery, imaging)

<> Cytimmune (USA) : colloidal gold-based nanomedicines

<> Debiotech (Switzerland) : Insulin Nanopump

<> Ferropharm (Germany) : superparamagnetic nanoparticles as contrast agents for Magnetic Resonance Imaging (MRI)

<> Magforce Nanotechnologies (Germany) : Nano-Cancer therapy

<> MedNanotech / Medical Nanotechnologies Inc (USA) : nanoparticle functionalization, drug delivery and targeted hyperthermic therapy

<> Minerva Biotechnologies (USA) : biochips based on affinity nanoparticles for diagnosis, therapy selection, and monitoring of drug effectiveness (example : test which identifies the MUC1* biomarker)

<> NanoBioMagnetics (USA) : organ-assisting-device (OAD) technologies employing magnetically responsive nanoparticles (MNP)

<> Nanobiotix (France) : NanoXray nanoparticles

<> NanoMedical Systems (USA) : Personalized Molecular Drug delivery System

<> NanoSpectra Biosciences (USA) : Aurolase therapy for thermal destruction of solid tumors

<> Nanosphere (USA) : advanced molecular diagnostics systems

<> NanoViricides (USA) :  targeted anti-viral therapeutics utilizing nanoscale materials and processes

<> NOD Pharmaceuticals (USA/China) : Nanoparticle Oral Delivery technology

<> Omega Genesis (USA) : focused on nano-scale materials that promote or inhibit angiogenesis (the growth of new blood vessels)

<> Savara Pharmaceuticals (USA) : NanoCluster dry powder aerosol drug delivery platform

<> Shrink Nanotechnologies (USA) : StemDisc platform, ShrinkChip rapid prototyping system

Comments are welcome for expanding this list !

<<< Latest post update : 23/10/2010 >>>

Nanotech versus biotech : visibility in “Le Monde” archive

This chart was built by searching the French newspaper “Le Monde” archive for articles mentioning nanotechnologies/biotechnologies. See this post for comparison with nanotech/biotech in the New York Times archive.


Nanotech versus biotech : visibility in the New York Times archive

This chart was built by searching the New York Times archive for articles mentioning nanotechnology/biotechnology. It can be clearly seen that biotech is a more mainstream subject (~5 to ~15 times more visible than nanotech) but is surprisingly losing visibility from year to year…


Carbon nanotubes can dramatically accelerate the germination and growth of plants

In the frame of a new study entitled Carbon Nanotubes Are Able To Penetrate Plant Seed Coat and Dramatically Affect Seed Germination and Plant Growth recently published in the online edition of ACS Nano, researchers have demonstrated that carbon nanotubes can penetrate thick seed coat and support water uptake inside tomato seeds. According to some of the authors : “The fact that nanomaterials have a strong influence on the growth kinetics of the plants is a clear indication of the bio-activity of these nanomaterials (…) The activated process of water uptake could be responsible for the significantly faster germination rates and higher biomass production for the seeds and seedlings that were exposed to carbon nanotubes [CNT], although the exact molecular mechanisms of CNT-induced water uptake inside plants seeds are not clear yet and require further investigation (…)” (see Nanowerk article and original publication for further details)

[[[ Additional link suggested by Nanocolors :

# Carbon nanotubes in sci-tech publications since 2000 ]]]