A nanotech sensor to distinguish between the breath of lung cancer patients and healthy controls


Israeli researchers have demonstrated that an array of sensors based on functionalized gold nanoparticles in combination with pattern recognition methods can distinguish between the breath of lung cancer patients and healthy controls. Their study was published online in Nature Nanotechnology on August 30th in an article entitled “Diagnosing lung cancer in exhaled breath using gold nanoparticles” (abstract).

The gold nanoparticles are functionalized with different organic groups that respond to various Volatile Organic Compounds (VOCs) relevant to lung cancer ; when exposed to biomarkers, the molecularly modified gold particles move apart and, as a result, the resistance of the organic film at their surface increases differently, depending on several factors. Pattern recognition algorithms can then be used to obtain information on the identity, properties and concentration of the vapor exposed to the sensor array from the resistance patterns.  

According to one of the authors of the study : “Our results show great promise for fast, easy, and cost-effective early diagnosis and screening of lung cancer, including different types of primary lung cancer“.

(source : Nanowerk article)

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One Response

  1. […] # A nanotech sensor to distinguish between the breath of lung cancer patients and healthy controls […]

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